Many categories of medications that assist to reduce pain and improve function include: Anti-inflammatories (e.g. Advil, Naproxen), antidepressants (e.g. Cymbalta), anticonvulsants (e.g. pregabalin, gabapentin), cannabinoids (e.g. Nabilone), and opiate analgesics (e.g. morphine).The medications prescribed may also be helpful to improve sleep and mood. They are frequently used in conjunction with other modalities for the treatment of difficult chronic pain patients.